Extracorporeal Blood Oxygenation and Ozonation (EBOO) is an advanced intravenous therapy that combines blood filtration, oxygenation, ozonation, and ultraviolet (UV) light exposure in a closed-circuit system. During EBOO, blood is gently withdrawn from the body, passed through a specialized filter where it is exposed to medical-grade oxygen, ozone, and UV light, and then safely returned to the body—all without exposure to outside elements. This process is similar in appearance to hemodialysis but is distinct in its purpose and method. (1, 3, 5, 12).
EBOO is sometimes referred to as “ozone dialysis” because it treats a larger volume of blood (up to 2–3 liters per session) compared to traditional ozone IV therapies, which typically treat much smaller amounts.
Dual Vein Access: Blood is drawn from one vein and reintroduced through another, allowing for continuous circulation during the session.
Filtration, Ozonation, and UV Light: The blood passes through a dialysis-like filter, where it is exposed to a controlled concentration of ozone and oxygen, as well as full-spectrum UV light. This step helps remove toxins, infuse the blood with oxygen and ozone, and neutralize pathogens (4, 10, 12).
Return to the Body: The treated blood is then returned to the patient, completing the circuit.
A typical EBOO session lasts about one hour. The process is performed under medical supervision, and most patients can resume normal activities immediately afterward (3, 5, 7).
Oxygen and ozone are central to the EBOO process, each offering unique and complementary effects:
Why Oxygenation Matters
Enhanced Cellular Energy: Oxygen is essential for cellular respiration, the process by which cells produce energy. Increased oxygenation supports energy, reduces fatigue, and promotes overall vitality (1, 6, 7, 8).
Accelerated Healing and Recovery: Higher oxygen levels can speed up tissue repair and recovery from injuries or surgery, making EBOO attractive for athletes and those recovering from illness (1, 6, 8).
Improved Brain Function: Oxygen therapy may support cognitive function, memory, and mental clarity (1, 6).
Stronger Immune System: Adequate oxygenation helps the body fight infections and strengthens immune responses (1, 6, 8).
Reduced Inflammation: Oxygen has anti-inflammatory effects, which can help manage chronic pain and inflammatory conditions (5, 7, 8).
Better Circulation and Cardiovascular Health: Improved oxygen delivery supports heart health and tissue healing (5, 7, 12).
Detoxification: Oxygen helps the body eliminate metabolic waste and toxins, supporting natural detoxification processes (1, 5, 7, 19).
Immune System Support: Ozone may activate and modulate the immune system, helping the body respond to infections and inflammation (1, 5, 8, 10).
Antimicrobial Effects: Ozone can inactivate bacteria, viruses, and fungi, supporting the body’s natural defenses (5, 8, 10, 18).
Anti-Inflammatory Properties: Ozone therapy may help reduce inflammation and pain, particularly in conditions like arthritis and autoimmune disorders (5, 7, 8, 18).
Improved Circulation: Ozone can help open blood vessels, improve blood flow, and support tissue oxygenation (5, 7, 12).
Detoxification: Ozone therapy may aid in breaking down toxins and metabolic waste, supporting the body’s detoxification processes (1, 5, 7, 19).
Tissue Regeneration: Ozone may stimulate the body’s natural healing mechanisms, including the mobilization of stem cells and increased collagen production, important for tissue repair and recovery (5, 8).
For Athletes:
EBOO’s ability to increase oxygenation and reduce inflammation may support improved endurance, faster recovery, and reduced muscle fatigue, making it a potential adjunct for athletic performance and recovery (5, 6, 7, 8).
Modern EBOO machines often incorporate full-spectrum UV light (UVA, UVB, and UVC) as part of the detoxification process. As the blood passes through the system, it is exposed to UV light, which offers several potential benefits:
Pathogen Inactivation: UV light can help deactivate bacteria, viruses, fungi, and other pathogens, supporting the body’s natural defenses (4, 10, 12).
Enhanced Detoxification: UV exposure aids in breaking down toxins and biofilms, complementing the oxidative properties of ozone (4, 10).
Immune Modulation: UV light may help balance immune responses and reduce inflammation (4, 10).
Improved Oxygen Transport: UV light can enhance the blood’s ability to carry oxygen, supporting tissue oxygenation and vitality (4, 10).
The combination of ozone and UV light creates a synergistic effect, further supporting the body’s detoxification and immune processes (4, 10).
EBOO is being studied and used in clinics for a variety of potential health benefits. While research is ongoing and not all claims are fully established, published studies and clinical experience suggest EBOO may:
Enhance blood oxygenation and energy production (1, 5, 6, 7, 8)
Support immune function and help the body combat infections and chronic inflammation (1, 5, 8, 10)
Aid in detoxification and removal of toxins, heavy metals, and metabolic waste (1, 5, 7, 19)
Reduce inflammation and pain (5, 7, 8, 18)
Improve circulation and cardiovascular health (5, 7, 12)
Support chronic disease management, including chronic fatigue, autoimmune disorders, cardiovascular disease, and more (5, 12, 16)
Note: While EBOO therapy is considered safe when performed by trained professionals, it is not a substitute for conventional medical care. The therapy’s effectiveness for specific conditions is still being researched, and results may vary. Always consult with a qualified healthcare provider to determine if EBOO is appropriate for your needs (2, 5, 12).
Preparation: Eat a healthy meal with protein and nutritious fats, and stay well-hydrated before your session (7).
Procedure: The session takes about one hour. You will have two IV lines—one for blood withdrawal and one for reinfusion. The blood is filtered, ozonated, and exposed to UV light before being returned to your body (3, 5, 7).
Aftercare: Most patients can return to normal activities immediately. Some may feel energized, while others may feel relaxed or mildly fatigued. These responses are normal and may vary from session to session (7).
EBOO therapy may be considered for individuals seeking adjunctive support for chronic conditions, immune modulation, or general wellness. However, it may not be suitable for those with poor venous access or certain medical contraindications. Always consult with a licensed healthcare provider to discuss your individual health needs and risks (2, 5, 12).
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[ISCO3: Extracorporeal blood oxygenation-ozonation (EBOO)] 2
[The Longevity Clinic: Your Complete Treatment Guide To EBOO] 3
[IFHO: Guide for EBO2 for Longevity] 4
[Aspen Integrative Medical Center: What is EBOO?] 5
[IV Elements: Benefits of EBOO Ozone] 6
[Next Health: EBOO Therapy Treatment] 7
[Silver Lining Clinic: EBOO Ozone Therapy] 8
[The Osteopathic Center: Discover the Power of EBOO Therapy] 9
[Advanced IV Health: Discovering the 5 Benefits of EBOO Treatment] 10
[IV Elements: What is EBOO Treatment] 11
[The AIM Clinic: EBOO Therapy: IV Blood Detox] 12
[Leicester Ozone: Ozone Doses Explained] 13
[PubMed: Extracorporeal blood oxygenation and ozonation] 14
[Detoxity Spa: The Incredible Benefits of EBOO Therapy] 15
[American Regenerative Clinic: What are EBOO Treatments?] 16
[Integrative Healthcare Springfield: EBOO: Extracorporeal Blood Oxygenation & Ozone] 17
[Regenerative Medicine LA: EBOO Treatment] 18
[Burick Center: EBOO Therapy: The Future of Healing] 19
Disclaimer:
EBOO therapy is an emerging treatment and is not intended to diagnose, treat, cure, or prevent any disease. The information provided here is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional before starting any new therapy.
